UniqU· Circle

The v1 formula

Every ingredient, every dose, every reason

Nothing is hidden behind a proprietary blend. Members of the Circle vote on what stays, what changes, and what gets cut before v1 ships.

In v1ShortlistedProposed

In v1

Locked in for the first shipment, pending final manufacturing checks.

L-Leucine

2.5 g · Preserve lean muscle

In v1

Why it's here

GLP-1 users often lose meaningful muscle mass alongside fat. Leucine is the primary trigger for muscle protein synthesis and helps protect lean tissue when appetite and protein intake drop.

Evidence

Multiple RCTs show 2–3 g of leucine per meal increases muscle protein synthesis in adults, including in calorie-restricted states.

Creatine Monohydrate

3 g · Strength & cognitive support

In v1

Why it's here

One of the most-studied supplements in existence. Helps maintain strength and power output during reduced food intake, with emerging cognitive benefits.

Evidence

Over 700 peer-reviewed studies. ISSN position stand confirms safety and efficacy at 3–5 g daily.

Vitamin D3

1,000 IU · Bone, immune & mood

In v1

Why it's here

Deficiency is widespread in northern Europe and worsens with reduced food variety. Supports calcium absorption, immune function, and mood regulation.

Evidence

EFSA-approved health claims for bone, immune, and muscle function. NHS recommends supplementation in autumn/winter.

Vitamin K2 (MK-7)

90 mcg · Directs calcium to bone

In v1

Why it's here

Pairs with D3 to direct calcium toward bone rather than soft tissue. Particularly relevant when bone turnover may be affected by weight loss.

Evidence

RCTs show MK-7 improves bone mineral density markers over 12+ months at this dose range.

Magnesium Glycinate

200 mg · Sleep, nerves & muscle

In v1

Why it's here

Glycinate form is well-absorbed and gentle on the gut — important when GI tolerance is already a concern. Supports sleep quality and reduces cramping.

Evidence

EFSA-approved claims for muscle function, nervous system, and reducing tiredness. Glycinate form has best tolerability profile.

Omega-3 (EPA + DHA)

1,000 mg combined · Heart, brain & inflammation

In v1

Why it's here

Reduced overall food intake often means reduced oily-fish intake. EPA and DHA support cardiovascular and cognitive health and help moderate inflammation.

Evidence

EFSA-approved heart-health claim at 250 mg/day. Meta-analyses support 1 g/day for cardiovascular outcomes.

Shortlisted

Strong case, under final review. Members are voting now.

Psyllium Husk

5 g · Digestive regularity

Shortlisted

Why it's here

GLP-1 medications slow gut motility, which can cause constipation. Soluble fibre helps regularity without harsh stimulants.

Evidence

Cochrane reviews support psyllium for chronic constipation. Well-tolerated at 5–10 g daily with adequate water.

Choline (as Citicoline)

250 mg · Liver & cognitive support

Shortlisted

Why it's here

Choline is essential for liver health and is often under-consumed. Citicoline form has cognitive benefits in early evidence.

Evidence

EFSA-approved claims for normal liver function and lipid metabolism. Citicoline trials show modest cognitive effects.

Proposed

On the table, but evidence is still being weighed.

Collagen Peptides

10 g · Skin, hair & joint comfort

Proposed

Why it's here

Rapid weight loss can affect skin elasticity and joint comfort. Collagen peptides are popular but evidence remains mixed at the dose required.

Evidence

Some RCTs show benefits at 10 g+ daily over 12 weeks for skin elasticity and joint pain. Quality varies.

Have a say in what ships

Members vote on every ingredient and dose. Join the Circle to add your voice — and lock in the founding price for life.

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